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100 Overexpression of the multifunctional adiponectin omentin-1 inhibits ER stress in the colon tissue of UC mice and attenuates colon injury and inflammatory cell infiltration

The accumulation of altered key tumor suppressor genes such as TP53 and CDKN2A, which encode p53 and p16INK4A, respectively is associated with the onset, progression and poor prognosis of HPV-negative HNSCC

Furthermore, a January 2025 retrospective study published in Gynecologic Oncology Reports highlighted NAC's potential in addressing endothelial damage

Mitochondrial Ca 2+ overload also triggers apoptotic cell death by increasing ROS production and opening the mPTP [96]

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