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PMCID: PMC6822791

This cell death mechanism is now receiving widespread attention, extending well beyond its original identification in cancer research, including in the field of drug-induced liver injury

Subsequently, the binding affinity of native semaglutide and GLP-1R ECD was calculated by Prodigy [45, 46] to be 3.4 10 6 M at 37 C, with the template being PDB entry: 4ZGM [29], where a total of 42 residue pairs were found to be located at the binding interface of semaglutide and GLP-1R ECD [29, 52], as listed in supplementary file 4zgm.ic

Each of these drugs is also marketed under a different name for the treatment of diabetes: semaglutide (Ozempic), tirzepatide (Mounjaro), and liraglutide (Victoza)

The TEM, EDX, and XRD techniques characterized the as-prepared nanoparticles

Often used as a brain "booster" due to its multiple cognitive improvements