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The main goal is preventing problems (like anemia, neuropathy, etc.) that would occur if you were low in these vitamins

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This single reaction sits at the intersection of two critical metabolic axes: The folate cycle axis: 5-MTHF is the methyl donor that MTR uses to regenerate methionine from homocysteine, simultaneously regenerating tetrahydrofolate (THF) that feeds back into one-carbon metabolism for nucleotide synthesis (thymidylate and purine biosynthesis)

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Monitoring and Biomarker Targets During a MOTS-C Protocol A MOTS-c dosage protocol without biomarker monitoring is an incomplete intervention

Marques, E., Kramer, R