Helen I have a background in biochemistry, but due to my brain having slowed down so drastically, it took me 3 months to figure out what was going on what should have taken me no more than 3 hours
Q: What should I bring to my B12 consultation
Gut Microbiome Effects Research suggests compounds such as 5-Amino-1MQ may alter the gut microbiome in models
The first few weeks produce modest changes as the dose titrates up
A Cochrane review supports the use of high-dose vitamin B 12 (1 mg and 2 mg daily) in elevating serum vitamin B 12 level and achieving haematological and neurological responses, even in patients with PA or with ileal resection.58 The recommendation for oral replacement is 1 mg daily for a month, and then 125 to 250 g daily as maintenance dose for patients with dietary insufficiency and food-cobalamin malabsorption, while for PA the maintenance dose is 1 mg daily.29 Vitamin B 12 does not have side-effects even when prescribed in large doses.59 However, hypokalaemia, resulting from uptake of circulating potassium by newly growing and dividing haematopoietic cells, can be severe or sometimes life-threatening
It is a specific 16-amino acid fragment of human growth hormone, corresponding to the region between amino acids 176 and 191