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Neurologic Diseases The nervous system, particularly the brain, is highly vulnerable to oxidative damage due to its high energy and oxygen consumption, the large concentration of PUFAs in myelin membranes, and its relatively low antioxidant defenses [180,181]

Therefore, the main question is could autophagy activation or necroptosis inhibition potentially affect the anticancer activity of CP

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Therefore, it is advisable to consult a healthcare practitioner to determine an individualised dosage suitable for specific needs and goals

To test the hypothesis, we applied ferroptosis inhibitor Ferrostatin-1 (Ferr-1), necrosis inhibitor Necrostatin-1 (Nec-1), or apoptosis inhibitor Z-VAD-FMK to treat VRK2-KO cells exposed to APR-017

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