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These medications may still be covered for their FDA-approved diabetes indications, but using them off-label for weight management is increasingly difficult to get approved

doi:10.1038/nrcardio.2014.173 49

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527 However, excess iron in macrophages can have adverse effects, such as exacerbating the process of atherosclerosis

Incretin-based weight loss pharmacotherapy: can resistance exercise optimize changes in body composition