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Archived from the original on 11 April 2019

NaBPC157 exhibited an anti-convulsant effect interacting with the GABAergic system and improved the diazepam efficacy when coadministered (10 g/kg, 10 ng/kg i.p.) with diazepam (5.0 mg/kg i.p., twice daily for 10 days)

The 2019 approval, detailed in a 2020 drug review in the Annals of Pharmacotherapy , represented one of the first times the FDA had formally addressed female sexual desire as a clinical target

World J Pharm Pharm Sci 5(2):5162 Ajlan A (2016) Medicinal plants: a review

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This suggests Dihexa works by restoring deficient synaptic density rather than enhancing already-optimal connectivity, which shifts the dose calculation: someone with pre-existing cognitive deficits may respond to 1mg, while someone with no deficits may see no effect at 5mg