It aims to dissect the molecular pathways, evaluate the animal model data, and critically assess the state of human research to equip clinicians with a balanced and actionable perspective
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In several experimental models of autoimmune diseases (including thyroiditis), EVOO components, oleic acid, hydroxytyrosol, oleuropein, and oleocanthal, have proven effective in counteracting inflammatory and oxidative imbalances, suggesting their efficacy in preventing autoimmune diseases [62, 136, 137]
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Indeed, NRF2 was found constitutively active in intestinal stem cell (ISC) in , and KEAP1-mediated NRF2 repression was required for ISC proliferation