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adults are affected by chronic metabolic conditions4, including Type 2 diabetes, obesity, fatty liver disease, kidney disease, and cardiovascular disease, contributing an estimated $1 to $1.5 trillion in annual healthcare spending5

Accordingly, it is reported that glutamate supplementation of up to 1-2 mM enhanced IFNy and IL-10 secretion by activated adult human peripheral T cells in vitro , whereas secretion of T H 2 cytokines IL-4 and IL-5 was unaffected (180)