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A reduced sulfhydryl form of GSH can be converted to the oxidized glutathione disulfide (GSSG) or S-nitrosoglutathione (GSNO) forms under oxidative or nitrosative conditions, respectively [52,53]

showed by using resonance synchronous spectroscopy that GSSH was 50-fold more reactive than H 2 S relative to H 2 O 2 at physiological pH ( k values estimated for GSSH and H 2 S were 23.76 and 0.46 M 1 s 1 , respectively) [62]

& Burant, C

Biochem Soc Trans 36:11201123

Statistical analysis All data were statistically analyzed using GraphPad Prism 9.5.1 software and expressed as mean standard error of the mean (SEM)

In INS-1 pancreatic beta cells, GLP-1 treatment reduced the oxidative damage caused by tert-butyl hydroperoxide