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The first week on semaglutide guide covers what to expect during the initial period

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The reality is that shifts in estrogen, progesterone, and cortisol can show up in your 30s, 40s, and beyond, often in ways that are easy to dismiss at first until they start affecting your day-to-day life

The STEP 1 trial showed semaglutide produced average weight loss of 14.9% of body weight over 68 weeks, compared with 2.4% with placebo