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These observations suggest that a defective transsulfuration pathway with reduced production of Ctt, H 2 S, or taurine, may be sufficient to recapitulate the outcomes induced by HNF4 deficiency in epithelial liver cancer cells

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Although less effective after 12 hours, some benefit can be gained by administration up to 24 hours, or even 72 hours in some cases, after overdose

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The GLOBOCAN 2020 projection projected 19.3 million new cancer diagnoses and over 10 million cancer-related deaths in 2020 (Sung et al., 2021)

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