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Bernal W, Hyyrylainen A, Gera A, et al

Naturally present in plasma, saliva, and urine, its levels decline with age, correlating with slower healing and visible tissue degeneration

*Correspondence: Kazuki Saito, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan e-mail: [email protected] This article was submitted to Plant Physiology, a section of the journal Frontiers in Plant Science

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occasional mild injection-site redness , sensitivity, or transient stinging may occur

Materials and methods Docking and system Preparation The X-ray crystal structure and sequence of tyrosinase bound with tropolone and copper (PDBID: 2Y9X) were obtained from the RCSB Protein Data Bank ( 49