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Chronic high-dose vitamin B intake (generally in gram quantities daily over many months) has been linked to severe sensory neuropathy characterized by numbness, impaired proprioception, and paresthesia in a stocking-glove distribution

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doi: 10.3389/fonc.2025.1613751 Received 17 April 2025 Accepted 29 September 2025 Published 24 October 2025 Volume 15 - 2025 Edited by Stefano Cairo, Champions Oncology, Inc., United States Reviewed by Janith Ananda Seneviratne, Peter MacCallum Cancer Centre, Australia Nevim Aygun, Ege University, Trkiye Updates Copyright 2025 Epp, Egan, Poon, Abdul Aziz, Wynne, Chesler, Halasz and Kolch