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10.5009/gnl18490 [DOI] [PMC free article] [PubMed] [Google Scholar] Sikiric P., Jadrijevic S., Seiwerth S., Sosa T., Deskovic S., Perovic D., et al

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Collectively, the results of this study illustrate that AOD9604 exerts distinct metabolic effects depending on the genetic background of the animal and the presence of functional 3-ARs

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The bottleneck logic is worth restating because it explains when stacking helps at all: adding a second compound only matters if it clears a different rate-limiting step than the ones already covered