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These facts led to the search for and design of GST inhibitors, including their synthetic analogues and glutathione conjugates, however, most of the existing inhibitors are either too toxic to be used in vivo or are effective only in vitro [14, 15]

Follow up visits with the physician are scheduled regularly to ensure the patient is on track to losing weight

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Additionally, rapid weight loss itselfregardless of the methodhas been associated with mood changes in some individuals, potentially due to hormonal shifts, nutritional factors, or psychological adjustment challenges