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According to the American Academy of Dermatology, 90% of melasma occurs in women, and its most common among women between the ages of 20 and 40
But did you know it can also be found in foods such as red meat, poultry, and dairy products
75 participants (25 in each group) completed the study
Upon tissue disruption, danger-associated molecular patterns (DAMPs) Such as extracellular ATP, high-mobility group box 1 (HMGB1), and uric acid crystals are released from damaged cells [26, 27], while PAMPs from the wound microbiome including lipopolysaccharide (LPS) from Gram-negative bacteria, lipoteichoic acid from Gram-positive bacteria, and bacterial DNA-are detected by pattern recognition receptors (PRRs) such as NLRP3, AIM2, or NLRC4 [28]
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