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Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial
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For instance, a high dosage of IGF-1 (100 ng/mL) was found to be detrimental in a mouse study, inducing ectopic ossification and impairing Achilles tendon healing
[3] For chronic conditions such as inflammatory bowel disease or persistent gut permeability, longer-duration protocols of eight to twelve weeks have been explored in preclinical literature