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Specifically, the IGF-1-PI3K-Akt-mTOR cascade promotes protein synthesis and suppresses protein degradation by phosphorylating downstream FoxO, thereby inhibiting E3 ligases (MuRF1 and atrogin-1) (73,81)

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GLP-1, or glucagon-like peptide-1, is a hormone naturally produced by the body that plays a crucial role in regulating appetite, digestion, and overall metabolic processes

Wang SY, Li MM, Wang L, Pan J, Sun Y, Wu JT, et al

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The least likely winner is the impatient lifter taking random doses for two weeks while still missing meals, sleep, and training progression