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Manage temperature changes Stay cool : Avoid extreme temperatures and sudden changes in temperature

*Correspondence: Vitalij Novickij, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The Multiple Fold (mfold) web server is a widely used bioinformatics tool for identifying secondary structures of ssDNA (73), using thermodynamic approaches like Turners thermodynamics table and free-energy minimization algorithms to forecast hybridization and melting temperatures (74)

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Thus, one-third of the controls showed Hamilton Depression Rating Scale (HAMD) [53] values between 7 and 12