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In another study, liraglutide was shown to prevent the onset of endoplasmic reticulum stress in HUVECs exposed to high glucose via dose dependent induction of mitochondrial fusion marker, OPA1, thereby inhibiting mitochondrial fragmentation and apoptosis [104]

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Effect of insulin glargine up-titration vs insulin degludec/liraglutide on glycated haemoglobin in patients with uncontrolled type 2 diabetes: the DUAL randomized clinical trial

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