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For cell sorting, cell suspensions were stained with FITC-conjugated human Ep-CAM antibody and Alexa Fluor APC-conjugated human C-Kit for 30 minutes on ice

Garber JR, Cobin RH, Gharib H, Hennessey JV, Klein I, Mechanick JI, et al

Science 376 , 14711476 (2022)

The toxins, enzymes and metabolites of bacteria (predominantly Gram-negative anaerobic) present in the dental plaque play a key role in the initiation of the inflammatory process, but the exact pathomechanism is far from being understood in detail (5-8)

Full skin lightening results appear within 3 to 6 months of regular sessions, but support sessions and a special lifestyle are required to maintain these results

By the end of a full course, some describe the underlying condition as changed rather than just managed