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Disease management involves a multidisciplinary approach, including lifestyle modifications, medication, and specialized care (Rossing et al., 2022)

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3.5 Insulin-like growth factor binding protein 5 (IGFBP-5) IGFBP-5 is a key IGFBP family member that regulates IGF-1 and IGF-2 activity and exerts IGF-independent functions on cells (Zhu et al., 2024)