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It is very normal to experience a loss of appetite

Some patients experience nausea or digestive discomfort early on

They suppress glucagon secretion from pancreatic alpha cells, slow gastric emptying to reduce postprandial glucose excursions, and promote satiety through central nervous system pathways

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Not a substitute for approved therapy

Despite the recognition and appreciation of translational electrophysiology by European and United States societies for heart rhythm disorders [166, 167], a relevant gap is evident between current patient therapy on one side and the implementation of basic research knowledge into clinical decision making on the other