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Increased reliance on fatty acid oxidation (FAO) alters mitochondrial electron flux and redox cofactor dynamics, influencing both anaboliccatabolic balance and oxidative buffering capacity

The STEP-1 follow-up data for Semaglutide showed that participants who discontinued the medication regained approximately two-thirds of their lost weight within one year without significant lifestyle intervention

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The reductions in MI, stroke, and CV death suggest a targeted impact on atherosclerotic processes, rather than acute hemodynamic effects

Potential Cardiovascular Benefits Current studies are exploring how it may reduce heart risks, especially in patients with obesity and diabetes