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How GLP-1 medications help GLP-1 receptor agonists slow gastric emptying (food stays in your stomach longer), increase satiety signals to your brain, and reduce appetite

De Mesquita YLL et al

Dhillon, S

GLP-1 Receptor Activation Only Reduces appetite through hypothalamic signaling Slows gastric emptying to increase fullness duration Enhances glucose-dependent insulin secretion Suppresses glucagon release after meals Retatrutide adds two additional receptor targets

Body Composition Changes During Weight Reduction With Tirzepatide in the SURMOUNT-1 Study of Adults With Obesity or Overweight

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