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Individuals with certain medical conditionssuch as kidney or heart diseasemay require special considerations or alternative wellness strategies

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Reconstitution with an appropriate sterile diluent (bacteriostatic water or sterile water for injection) is required before use

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TM6 undergoes the characteristic outward rotation that opens the G protein-binding cavity, TM5 repositions to form the lateral wall of this cavity, and the intracellular ends of TM3 and TM7 reorganize to complete the G protein docking surface

Novo already markets an oral form of semaglutide