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It is important to note the additive character of clearance

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Free Radic Biol Med 27:922935 Griffith OW, Mulcahy RT (1999) The enzymes of glutathione synthesis: -glutamylcysteine synthetase

This upregulation of GATA3 promotes OC cell migration and invasion, enhances resistance to paclitaxel drugs and ultimately affects the prognosis of patients with advanced OC (77)

This predisposition screening does not predict exact medication response or guarantee long-term success, but may help your provider make more informed decisions about dosing intensity, monitoring strategy, and therapy duration