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Aerobic eukaryotes have developed antioxidant defense mechanisms which act by mitigating damaging effects of excessive ROS production, hence under physiological conditions there is a dynamic balance between the ROS generation and elimination [22]

A peripheral neuropathy caused by diabetes It is typical for microvascular disorders of the eyes, kidneys, and peripheral nerves to develop resulting from both type 1 and type 2 diabetes persistent hyperglycemia (45)

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