The primary end point was PFS, while the secondary end points were OS, response rate, and safety.[22][Level of evidence B1] The median PFS was 18.3 months in the lenvatinib group and 3.6 months in the placebo group (HR progression or death , 0.21
PMID 6137189
Subsequent multiple linear regression analysis, using muscle mass loss as the dependent variable and Semaglutide dosage, baseline ASMI, handgrip strength, and gait speed as independent variables, confirmed independent associations for semaglutide dosage, baseline ASMI, and gait speed, whereas handgrip strength lost statistical significance
however, they may receive a stronger class of recommendation in future guidelines, thus the box is shaded red with a green border
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Gallstones and gallbladder inflammation can also occur