In parallel, the effect of the drugs were simulated using an adapted version of the singleGeneDeletion of the COBRA toolbox [28] (Drug Deletion function): Therefore, DrugBank v5.1.3 [29] was mined to identify 1175 drugs inhibiting metabolic genes (genes present in Recon 2.04) and their targets that were then used as input for the Drug Deletion function
Comparative effects of GLP-1 and GLP-2 on beta-cell function, glucose homeostasis and appetite regulation
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Impurities from the synthesis processthings like leftover reagents or truncated amino acid sequencescan create instability in the final product
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