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Furthermore, although damage to sperm resulting in infertility, including DNA damage, caused by mitochondrial stress remains a key hypothesis, the mechanistic basis for these changes remains unknown, especially because we did not exclude patients with high levels of oxidative stress or high DNA fragmentation

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The funder was involved in the design of this study, interpretation, and writing of the manuscript

It is worth noting that this cardioprotective effect of exenatide outweighed the fact that a greater proportion of patients on exenatide treatment possessed CVD risk factors such as prior ischemic heart disease, obesity, hyperlipidemia, and hypertension [98]

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Arch Biochem Biophys 429(2):123133 Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K et al (1999) Distinct roles of thioredoxin in the cytoplasm and in the nucleus a two-step mechanism of redox regulation of transcription factor NF-B