Those remain separate questions, distinct from the molecular science described here.
Zero Stimulants: Provides energy and fat-burning benefits without caffeine or other stimulants
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimers disease
Meader E, Mayer MJ, Steverding D, Carding SR, Narbad A
New England Journal of Medicine 376, 17131722
In agreement with expectations, the first outcome trial of a GLP-1RA, the ELIXA trial of the short-acting lixisenatide, an exendin-4 derivative with properties almost identical to those of exendin-4 or exenatide (stable, full agonists of the GLP-1 receptor), showed no increased cardiovascular risk in a patient group with severely increased CVD risk