Glutathione is part of the antioxidant defense system of the cell, together with superoxide dismutase, catalase, glutharedoxin, thioredoxin, alpha-D-tocopherol (vitamin E), ascorbic acid (vitamin C), and others
Individuals with an intact blood-brain barrier (BBB) are usually protected from higher dietary intake of free glutamate due to saturation of the glutamate transporter at the BBB, thereby limiting the amount of glutamate able to access the CNS (64)
However, we now know that G6PT deficiencies are inherited as autosomal recessive traits and HPRT and PRPS defects are X-linked recessive traits
Speight J
Well also highlight why L-glutathione is often preferred and what to look for when buying online or in-store
Trends Immunol (2006) 27(1):2431