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Blood circulation improves oxygen and nutrient delivery to damaged tissue (microvascular repair, localized injury zones)

Phase 3 REDEFINE trials showed 20.4% weight loss at 68 weeks

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Observational studies A large number of cross-sectional and prospective cohort studies have associated elevated blood homocysteine concentrations with measures of poor cognitive scores and increased risk of dementia, including Alzheimer's disease (reviewed in 67, 69)

Cancers 14 (3), 560