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Using an inducible, epidermal-specific c-Jun/JunB double-knockout (DKO*) mouse model that faithfully recapitulates psoriatic skin and arthritis, the authors reveal profound metabolic alterations characterized by reductions in dermal fat and circulating free fatty acids, as well as elevated -hydroxybutyrate [3]
2023 Ludvik B, Giorgino F, Jodar E et al (2021) Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial
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Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats
The second step is catalyzed by GSH synthase, which adds glycine to -glutamylcysteine to form GSH
