Sources: Institute of Medicine, Food and Nutrition Board, National Academies of Science, Dietary Reference Intakes (DRI): Recommended Dietary Allowances and Adequate Intakes , USA 2018, Mustafa Vakur Bor, Kristina M von Castel-Roberts, Gail PA Kauwell, Sally P Stabler, Robert H Allen, David R Maneval, Lynn B Bailey Ebba Nexo Daily intake of 4 to 7 g dietary vitamin B-12 is associated with steady concentrations of vitamin B-12related biomarkers in a healthy young population Am J Clin Nutr 2010 91: 3 571-577
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Oral administration is particularly relevant for targeting local gut injuries, as the peptide passes through the digestive system and reaches damaged areas
The NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, though there is generally no benefit to such excessive amounts without confirmed deficiency
Oral BPC-157 is uniquely effective here because the peptide is stomach-acid stable