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In tumor cells, Nrf2 plays an important role in cell proliferation by activating the pentose phosphate pathway (PPP), which provides nucleotides for genomic replication of mitotic tumor cells and the antioxidant NADPH for cytoprotection from oxidative stress provoked by the tumor environment [74]

Direct interactions with semaglutide are rare, but like amoxicillin, it can cause GI upset

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