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Rubbia-Brandt et al (2) reported that 78% of patients with metastatic colorectal cancer receiving OXA-based chemotherapy experience varying degrees of sinusoidal injury to the liver

Neuropharmacology 65, 6573

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Thus, while HTY demonstrates high gastrointestinal absorption, its pharmacological activity in vivo might be mediated predominantly by its conjugated metabolites rather than the parent compound to warrants further research on its metabolites vs