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Acknowledgements This work was partially supported by National Basic Research Program of China (973 Program

Loss of glucose-6-phosphate dehydrogenase (G6PD), a key enzyme in the pentose phosphate pathway, reduced melanoma metastasis without obvious impact on the formation of primary subcutaneous tumors [34]

The weight loss data is similar: For weight loss specifically, there is no meaningful clinical difference

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Tumors The physiological characteristics of tumor cells make them significantly different from normal tissue cells in terms of metal and energy metabolism