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Not everyone, however, was convinced that glucagon needed to be blocked to encourage weight loss

Blocking the degradation of GLP-1 by inhibiting DPP-4 is how certain types of diabetes medicine work

By unifying three incretinmetabolic pathways, it is being studied for multidimensional effects on appetite, glycemic control, energy expenditure, and body composition

Participants had lived with diabetes for around 2.5 years when the trial began, and had not taken any medications to treat their condition for at least 90 days

doi:10.1002/oby.24067 CDC

The Psychology of Long-Term Treatment Committing to ongoing medication for weight management requires a mental shift that many patients struggle with