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As a potent antioxidant, glutathione neutralizes harmful free radicals, protects against cellular damage, and aids in the bodys detoxification processes

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Firstly, the roles of GSH in cancer cells are introduced to demonstrate the importance of GSH exhaustion in anticancer therapy

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GSSCys and HEDS oxidoreductase assays Steady-state kinetics of wild type and mutant ScGrx7 and PfGrx in the GSSCys and HEDS assays were determined spectrophotometrically by monitoring the consumption of NADPH at 340 nm and 25 C using a thermostated Jasco V-650 UV/vis spectrophotometer 11,12,18