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Tirzepatide is administered by subcutaneous injection for the treatment of type 2 diabetes mellitus and chronic weight management in adults with obesity or overweight with weight-related comorbidities

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Research indicates these effects are not universal and vary significantly based on individual biology, baseline mental health status, and medication dosing patterns

So if you have an external stimulus that's slowing your digestion down, and then you have fat sitting in your stomach even longer, it might make you feel more nauseous

Thus in addition to increasing GLP-1 concentration, recent research shows that it also lowers insulin concentration and stabilizes ghrelin levels