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The original GLP-1 drugs, produced by companies like Novo Nordisk and Eli Lilly, are already involved in more than a thousand lawsuits under MDL 3094 in Eastern Pennsylvania for semaglutide and tirzepatide's adverse side effects

Cosmetic formulation outcomes may vary between individuals

If pigmented spots are accompanied by neck masses or lymphadenopathy, this suggests possible spread of cancer and requires urgent medical evaluation

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Clinical trial averages: Wegovy (semaglutide): ~15% of body weight Zepbound (tirzepatide): ~20% of body weight Some people lose considerably more