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Um meta-estudo que incluiu 9 estudos clnicos com 911 participantes confirmou que ao longo do tempo, em mdia, os participantes perderam alguma gordura (1,33 kg versus 0,57 kg), mas aps uma anlise de meta-regresso a perda de gordura foi prxima de zero
A 2011 in vivo study demonstrated that, in this mouse model, the administration of Pioglitazone induces a proadipogenic antitumor response, with the final result of preventing metastasis and reducing tumor size (Zhang et al., 2017) highlighting the importance of the use of this compound in that specific clinical setting
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