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10.1038/s41423-021-00757-x Cell Mol

These two peptides operate through entirely different biological pathways, which means their effects have the potential to complement each other rather than duplicate

1 2 3 "Isolation of NF-E2-related factor 2 (NRF2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region"

Therefore, the question of balanced enzyme concentration was brought up