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HILICpositive mode (HILIC-pos) Water-soluble metabolites were analyzed using a Shimadzu Nexera X2 UHPLC coupled to a Q Exactive Hybrid Quadrupole Orbitrap mass spectrometer (Thermo Fisher Scientific)

10.1371/journal.pone.0086075 75 KhanmohammadiM.KhanjaniS.EdalatkhahH.ZarnaniA

And between 75% and 87.5% depending on medication class fared better without the medication

This can lead to the diagnosis of vitamin D deficiency when it does not exist

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With new formulations and combination therapies being developed, these medications are setting a new standard for safe, effective, and sustainable results