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You can, but stability is the challenge

8.5.5.6 Predictive in vitro models A lack of robust and predictive in vitro models to assess the performance of these complex formulations remains a significant limitation

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Cardiac comorbidities at baseline were highly prevalent: 98.6% and 98.5% of patients had hypertension, 55.2% and 55.1% of patients had coronary artery disease, and 33.9% and 34% of patients had congestive heart failure, within the GLP1-RA and DPP4i groups, respectively

However, reported performance is platform- and cohort-dependent and should be interpreted as supportive evidence for multimarker modelling rather than as a clinic-agnostic benchmark, pending calibration and external validation across laboratories and protocols

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