Adult male mice were randomly assigned into three main groups (1-3) based on the neurobehavioural models
Highlights Sodium-glucose cotransporter-2 inhibitors (SGLT2-i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) provide modest but clinically meaningful blood pressure (BP) lowering effects in people with hypertension and cardiometabolic comorbidities
Leopold et al
Pflugers Arch 444:457466 Kelly A, Li C, Gao Z, Stanley CA, Matschinsky FM (2002) Glutaminolysis and insulin secretion: from bedside to bench and back
Some patients respond to lower doses, while others need the maximum dose to see results
Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, Munzel U, Yakhno N, Raz I, Novosadova M, Maus J