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192 A large meta-analysis concluded an intermittent fasting protocol based on 35 days per week of intensive calorie restriction was the most beneficial with regards to weight loss and metabolic improvement compared to regular diet or continuous calorie restriction

More than 10,000 people used tirzepatide in controlled clinical settings

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Figure 2 provides a synthesis of the molecular and immunological pathways shared by obesity and PsD, further pointing out the central role of adipokines in these conditions [2331]